SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02329

Signal sequence   MKPIQKLLAGLILLTWCVEGCSS

Length  23

Organism  Homo sapiens (Human)

UniProt ID  P01148,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02329.cif

Structure  SPKB02329.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2504.10224

Aliphatic index  135.6521739

Isoelectric point  8.227998218

Charge (pH=7)   0.875219923

Topological polar surface area  903.64

Aromaticity  0.043478261

Average rotatable bonds  3.608695652

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  34

X logP energy  -5.0781

Hydropathy 



Literature Information


Title  The chemical identity of the immunoreactive LHRH-like peptide biosynthesized in the human placenta.

DOI  10.1016/0006-291x(82)92047-2,

Publication Year  1982

PubMed ID  6760865,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.