General Information
SPKB ID SPKB02328
Signal sequence MSMLFYTLITAFLIGVQA
Length 18
Organism Mus musculus (Mouse)
UniProt ID P01139,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02328.cif
Physicochemical Information
Molecular weight 2019.48784
Aliphatic index 135.5555556
Isoelectric point 6.093198033
Charge (pH=7) -0.002866115
Topological polar surface area 682.03
Aromaticity 0.166666667
Average rotatable bonds 3.555555556
Number of hydrogen bond donors 24
Number of hydrogen bond acceptors 26
X logP energy -1.8431
Hydropathy 
Literature Information
Title Molecular and structural insight into proNGF engagement of p75NTR and sortilin.
DOI 10.1016/j.jmb.2009.12.030,
Publication Year 2010
PubMed ID 20036257,
Patent ID NA,
