General Information
SPKB ID SPKB02327
Signal sequence MPPSGLRLLPLLLPLLWLLVLTPGRPAAG
Length 29
Organism Homo sapiens (Human)
UniProt ID P01137,
Motif 1..29
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8REW,
Predicted Structure ID SPKB02327.cif
Physicochemical Information
Molecular weight 3075.87884
Aliphatic index 164.8275862
Isoelectric point 12.50010931
Charge (pH=7) 1.997977677
Topological polar surface area 1005.43
Aromaticity 0.034482759
Average rotatable bonds 3.068965517
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 35
X logP energy -1.51626
Hydropathy 
Literature Information
Title Latent high molecular weight complex of transforming growth factor beta 1. Purification from human platelets and structural characterization.
DOI NA,
Publication Year 1988
PubMed ID 3162913,
Patent ID NA,
