SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02326

Signal sequence   MRLAGWGLRWAIALLIAVGEA

Length  21

Organism  Bos taurus (Bovine)

UniProt ID  P01131,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02326.cif

Structure  SPKB02326.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2267.76344

Aliphatic index  149.047619

Isoelectric point  10.39777148

Charge (pH=7)   0.9997528

Topological polar surface area  838

Aromaticity  0.095238095

Average rotatable bonds  3.428571429

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  26

X logP energy  -2.38696

Hydropathy 



Literature Information


Title  Use of antipeptide antibodies to demonstrate external orientation of the NH2-terminus of the low density lipoprotein receptor in the plasma membrane of fibroblasts.

DOI  10.1083/jcb.97.5.1635,

Publication Year  1983

PubMed ID  6313699,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.