SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02324

Signal sequence   MKLITILLLCSRLLPSLA

Length  18

Organism  Rattus norvegicus (Rat)

UniProt ID  P01048,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02324.cif

Structure  SPKB02324.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1998.59984

Aliphatic index  200.5555556

Isoelectric point  9.833242293

Charge (pH=7)   1.935711238

Topological polar surface area  697.84

Aromaticity  0

Average rotatable bonds  3.722222222

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  26

X logP energy  -1.97853

Hydropathy 



Literature Information


Title  Purification and characterization of rat T-kininogens isolated from plasma of adjuvant-treated rats. Identification of three kinds of T-kininogens.

DOI  NA,

Publication Year  1988

PubMed ID  3121623,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.