SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02323

Signal sequence   MKLITILFLCSRLLPSLT

Length  18

Organism  Bos taurus (Bovine)

UniProt ID  P01045,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02323.cif

Structure  SPKB02323.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2062.64334

Aliphatic index  173.3333333

Isoelectric point  9.833242293

Charge (pH=7)   1.935711238

Topological polar surface area  718.07

Aromaticity  0.055555556

Average rotatable bonds  3.777777778

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  27

X logP energy  -2.42103

Hydropathy 



Literature Information


Title  Bovine high molecular weight kininogen. The amino acid sequence, positions of carbohydrate chains and disulfide bridges in the heavy chain portion.

DOI  NA,

Publication Year  1987

PubMed ID  3546295,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.