SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02316

Signal sequence   MGPTSGPSLLLLLLTHLPLALG

Length  22

Organism  Homo sapiens (Human)

UniProt ID  P01024,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02316.cif

Structure  SPKB02316.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2214.73474

Aliphatic index  164.0909091

Isoelectric point  7.550323994

Charge (pH=7)   0.08889339

Topological polar surface area  757.65

Aromaticity  0

Average rotatable bonds  3.045454545

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  29

X logP energy  -4.1082

Hydropathy 



Literature Information


Title  The adipsin-acylation stimulating protein system and regulation of intracellular triglyceride synthesis.

DOI  10.1172/JCI116733,

Publication Year  1993

PubMed ID  8376604,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.