General Information
SPKB ID SPKB02312
Signal sequence MERMLPLLALGLLAAGFCPAVLC
Length 23
Organism Homo sapiens (Human)
UniProt ID P01011,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 9D7K,
Predicted Structure ID SPKB02312.cif
Physicochemical Information
Molecular weight 2403.05844
Aliphatic index 148.6956522
Isoelectric point 6.135737489
Charge (pH=7) -0.124193321
Topological polar surface area 785.14
Aromaticity 0.043478261
Average rotatable bonds 3.260869565
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 30
X logP energy -1.86603
Hydropathy
Literature Information
Title The microheterogeneity of desialylated alpha 1-antichymotrypsin: the occurrence of two amino-terminal isoforms, one lacking a His-Pro dipeptide.
DOI 10.1016/0167-4838(89)90139-8,
Publication Year 1989
PubMed ID 2787670,
Patent ID NA,