SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02304

Signal sequence   MEFFKKTALAALVMGFSGAALA

Length  22

Organism  Escherichia coli (strain K12)

UniProt ID  P00805,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02304.cif

Structure  SPKB02304.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2274.76464

Aliphatic index  93.63636364

Isoelectric point  9.537300927

Charge (pH=7)   0.999169354

Topological polar surface area  804.22

Aromaticity  0.136363636

Average rotatable bonds  3.409090909

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  -4.5142

Hydropathy 



Literature Information


Title  The primary structure of L-asparaginase from Escherichia coli.

DOI  10.1515/bchm2.1980.361.1.105,

Publication Year  1980

PubMed ID  6766894,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.