General Information
SPKB ID SPKB02303
Signal sequence MDGWRRMPRWGLLLLLWGSCTFG
Length 23
Organism Homo sapiens (Human)
UniProt ID P00797,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02303.cif
Physicochemical Information
Molecular weight 2752.31114
Aliphatic index 84.7826087
Isoelectric point 10.43741523
Charge (pH=7) 1.936446134
Topological polar surface area 1005.56
Aromaticity 0.173913043
Average rotatable bonds 3.695652174
Number of hydrogen bond donors 39
Number of hydrogen bond acceptors 33
X logP energy -4.18549
Hydropathy
Literature Information
Title Isolation and characterization of recombinant human prorenin in Chinese hamster ovary cells.
DOI 10.1093/oxfordjournals.jbchem.a123347,
Publication Year 1991
PubMed ID 2016271,
Patent ID NA,