SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02302

Signal sequence   MRCLVVLLAVFALSQG

Length  16

Organism  Bos taurus (Bovine)

UniProt ID  P00794,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02302.cif

Structure  SPKB02302.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1720.16454

Aliphatic index  164.375

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  625.04

Aromaticity  0.0625

Average rotatable bonds  3.5

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  22

X logP energy  -3.05943

Hydropathy 



Literature Information


Title  Amino-acid sequence of the peptide segment liberated during activation of prochymosin (prorennin).

DOI  10.1111/j.1432-1033.1975.tb02141.x,

Publication Year  1975

PubMed ID  240697,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.