SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02301

Signal sequence   MKWLLLLSLVVLSEC

Length  15

Organism  Sus scrofa (Pig)

UniProt ID  P00791,

Motif  1..15



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02301.cif

Structure  SPKB02301.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1747.22744

Aliphatic index  194.6666667

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  590.29

Aromaticity  0.066666667

Average rotatable bonds  3.866666667

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  22

X logP energy  0.1594

Hydropathy 



Literature Information


Title  Synthesis, purification, and active site mutagenesis of recombinant porcine pepsinogen.

DOI  NA,

Publication Year  1989

PubMed ID  2494172,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.