SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02300

Signal sequence   MLRFLVFASLVLYGHS

Length  16

Organism  Rattus norvegicus (Rat)

UniProt ID  P00773,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02300.cif

Structure  SPKB02300.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1853.25554

Aliphatic index  140

Isoelectric point  9.351184298

Charge (pH=7)   1.088039665

Topological polar surface area  651.09

Aromaticity  0.1875

Average rotatable bonds  3.625

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  23

X logP energy  -1.78153

Hydropathy 



Literature Information


Title  Isolation and characterization of rat pancreatic elastase.

DOI  10.1021/bi00285a008,

Publication Year  1983

PubMed ID  6555050,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.