SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02298

Signal sequence   MKTFIFLALLGAAVAFP

Length  17

Organism  Bos taurus (Bovine)

UniProt ID  P00760,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02298.cif

Structure  SPKB02298.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1810.27084

Aliphatic index  132.3529412

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  566.38

Aromaticity  0.176470588

Average rotatable bonds  3.235294118

Number of hydrogen bond donors  19

Number of hydrogen bond acceptors  21

X logP energy  0.2037

Hydropathy 



Literature Information


Title  Covalent structure of bovine trypsinogen. The position of the remaining amides.

DOI  10.1016/0006-291x(66)90162-8,

Publication Year  1966

PubMed ID  5967094,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.