SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02296

Signal sequence   MGSNLSPQLCLMPFILGLLSGGVTT

Length  25

Organism  Homo sapiens (Human)

UniProt ID  P00751,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7JTN,

Predicted Structure ID  SPKB02296.cif

Structure  SPKB02296.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2550.08454

Aliphatic index  120.8

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  931.47

Aromaticity  0.04

Average rotatable bonds  3.24

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  36

X logP energy  -8.8917

Hydropathy 



Literature Information


Title  Complete primary structure for the zymogen of human complement factor B.

DOI  NA,

Publication Year  1984

PubMed ID  6546754,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.