General Information
SPKB ID SPKB02293
Signal sequence MRALLLLGFLLVSLESTLS
Length 19
Organism Homo sapiens (Human)
UniProt ID P00748,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02293.cif
Physicochemical Information
Molecular weight 2076.56564
Aliphatic index 184.7368421
Isoelectric point 6.410149741
Charge (pH=7) -0.000243889
Topological polar surface area 767.24
Aromaticity 0.052631579
Average rotatable bonds 3.684210526
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 27
X logP energy -3.71763
Hydropathy 
Literature Information
Title Amino acid sequence of the heavy chain of human alpha-factor XIIa (activated Hageman factor).
DOI NA,
Publication Year 1985
PubMed ID 3886654,
Patent ID NA,
