General Information
SPKB ID SPKB02292
Signal sequence MEHKEVVLLLLLFLKSGQG
Length 19
Organism Homo sapiens (Human)
UniProt ID P00747,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02292.cif
Physicochemical Information
Molecular weight 2154.63904
Aliphatic index 153.6842105
Isoelectric point 7.549136954
Charge (pH=7) 0.091853568
Topological polar surface area 805.76
Aromaticity 0.052631579
Average rotatable bonds 4
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 28
X logP energy -2.8169
Hydropathy 
Literature Information
Title Structural relationship between "glutamic acid" and "lysine" forms of human plasminogen and their interaction with the NH2-terminal activation peptide as studied by affinity chromatography.
DOI 10.1111/j.1432-1033.1975.tb09887.x,
Publication Year 1975
PubMed ID 122932,
Patent ID NA,
