SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02290

Signal sequence   MSALGAVIALLLWGQLFA

Length  18

Organism  Homo sapiens (Human)

UniProt ID  P00738,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02290.cif

Structure  SPKB02290.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1874.31454

Aliphatic index  168.3333333

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  637.13

Aromaticity  0.111111111

Average rotatable bonds  3.277777778

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  22

X logP energy  -1.1075

Hydropathy 



Literature Information


Title  Covalent structure of human haptoglobin: a serine protease homolog.

DOI  10.1073/pnas.77.6.3388,

Publication Year  1980

PubMed ID  6997877,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.