SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02289

Signal sequence   MWLLYLLVPALFCRAGG

Length  17

Organism  Homo sapiens (Human)

UniProt ID  P00736,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02289.cif

Structure  SPKB02289.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1923.40764

Aliphatic index  143.5294118

Isoelectric point  8.527213491

Charge (pH=7)   0.935155858

Topological polar surface area  618.05

Aromaticity  0.176470588

Average rotatable bonds  3.352941176

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  22

X logP energy  0.71157

Hydropathy 



Literature Information


Title  Complete amino acid sequence of the A chain of human complement-classical-pathway enzyme C1r.

DOI  10.1042/bj2410711,

Publication Year  1987

PubMed ID  3036070,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.