SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02286

Signal sequence   MLLQAFLFLLAGFAAKISA

Length  19

Organism  Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

UniProt ID  P00724,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02286.cif

Structure  SPKB02286.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2025.52294

Aliphatic index  149.4736842

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  676.46

Aromaticity  0.157894737

Average rotatable bonds  3.473684211

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  24

X logP energy  -0.9998

Hydropathy 



Literature Information


Title  Identification of an active-site residue in yeast invertase by affinity labeling and site-directed mutagenesis.

DOI  NA,

Publication Year  1990

PubMed ID  2113524,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.