SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02280

Signal sequence   MRFFVPLFLVGILFPAILA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P00709,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1HML,

Predicted Structure ID  SPKB02280.cif

Structure  SPKB02280.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2164.76624

Aliphatic index  164.2105263

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  631.44

Aromaticity  0.210526316

Average rotatable bonds  3.368421053

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  22

X logP energy  3.38407

Hydropathy 



Literature Information


Title  The complete amino-acid sequence of human -lactalbumin.

DOI  10.1111/j.1432-1033.1972.tb01812.x,

Publication Year  1972

PubMed ID  5049057,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.