SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02271

Signal sequence   MGLEKSLFLFSLLVLVLGWVQPSLG

Length  25

Organism  Rattus norvegicus (Rat)

UniProt ID  P00684,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02271.cif

Structure  SPKB02271.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2747.37454

Aliphatic index  159.6

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  935.82

Aromaticity  0.12

Average rotatable bonds  3.56

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -2.0306

Hydropathy 



Literature Information


Title  Rat pancreatic ribonuclease. II. Amino acid sequence.

DOI  10.1016/0005-2795(73)90020-2,

Publication Year  1973

PubMed ID  4710592,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.