SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02268

Signal sequence   MRGTRLMGLLLALAGLLQLGLS

Length  22

Organism  Bos taurus (Bovine)

UniProt ID  P00639,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  9FJU,

Predicted Structure ID  SPKB02268.cif

Structure  SPKB02268.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2297.88924

Aliphatic index  168.6363636

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  881.77

Aromaticity  0

Average rotatable bonds  3.636363636

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  30

X logP energy  -5.76926

Hydropathy 



Literature Information


Title  Bovine pancreatic deoxyribonuclease A. Isolation of cyanogen bromide peptides; complete covalent structure of the polypeptide chain.

DOI  NA,

Publication Year  1973

PubMed ID  4734471,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.