SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02266

Signal sequence   MRTLWIVAVCLIGVEG

Length  16

Organism  Vipera ammodytes ammodytes (Western sand viper)

UniProt ID  P00626,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02266.cif

Structure  SPKB02266.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1760.18594

Aliphatic index  158.125

Isoelectric point  6.232433001

Charge (pH=7)   -0.062218605

Topological polar surface area  635.04

Aromaticity  0.0625

Average rotatable bonds  3.5

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  22

X logP energy  -1.97883

Hydropathy 



Literature Information


Title  Ammodytoxin A, a highly lethal phospholipase A2 from Vipera ammodytes ammodytes venom.

DOI  10.1016/0167-4838(85)90312-7,

Publication Year  1985

PubMed ID  3986212,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.