SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02263

Signal sequence   MRTLWIVAVLLLGVEG

Length  16

Organism  Crotalus adamanteus (Eastern diamondback rattlesnake)

UniProt ID  P00623,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02263.cif

Structure  SPKB02263.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1770.20654

Aliphatic index  182.5

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  635.04

Aromaticity  0.0625

Average rotatable bonds  3.5625

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  21

X logP energy  -0.86253

Hydropathy 



Literature Information


Title  Amino acid sequence of phospholipase A2-alpha from the venom of Crotalus adamanteus. A new classification of phospholipases A2 based upon structural determinants.

DOI  NA,

Publication Year  1977

PubMed ID  873920,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.