SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02261

Signal sequence   MHPAHLLVLLAVCVSLLGASDIPPLPL

Length  27

Organism  Oxyuranus scutellatus scutellatus (Australian taipan) (Coastal taipan)

UniProt ID  P00615,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02261.cif

Structure  SPKB02261.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2790.46134

Aliphatic index  173.3333333

Isoelectric point  6.488318012

Charge (pH=7)   -0.881725751

Topological polar surface area  919.88

Aromaticity  0

Average rotatable bonds  3.037037037

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  35

X logP energy  -2.8243

Hydropathy 



Literature Information


Title  Structural analysis of trimeric phospholipase A2 neurotoxin from the Australian taipan snake venom.

DOI  10.1111/j.1742-4658.2012.08691.x,

Publication Year  2012

PubMed ID  22776098,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.