General Information
SPKB ID SPKB02257
Signal sequence MRPSGTAGAALLALLAALCPASRA
Length 24
Organism Homo sapiens (Human)
UniProt ID P00533,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 3QWQ,
Predicted Structure ID SPKB02257.cif
Physicochemical Information
Molecular weight 2282.74774
Aliphatic index 114.5833333
Isoelectric point 10.52640717
Charge (pH=7) 1.936002961
Topological polar surface area 899.53
Aromaticity 0
Average rotatable bonds 2.916666667
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 32
X logP energy -10.21156
Hydropathy
Literature Information
Title Signal peptide prediction based on analysis of experimentally verified cleavage sites.
DOI 10.1110/ps.04682504,
Publication Year 2004
PubMed ID 15340161,
Patent ID NA,