SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02254

Signal sequence   MLGKSQFDDLFEKMSRKVAGHTSRRGFIGRVGTAVAGVALVPLLPVDRRGRVSRANA

Length  57

Organism  Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1) (Methylobacterium extorquens)

UniProt ID  P00372,

Motif  1..57



Activity Information


Pathway  Tat

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Tat/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02254.cif

Structure  SPKB02254.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  6153.18654

Aliphatic index  87.19298246

Isoelectric point  12.29940015

Charge (pH=7)   7.091096374

Topological polar surface area  2634.04

Aromaticity  0.052631579

Average rotatable bonds  3.649122807

Number of hydrogen bond donors  96

Number of hydrogen bond acceptors  84

X logP energy  -29.17884

Hydropathy 



Literature Information


Title  Amino acid sequence studies of the light subunit of methylamine dehydrogenase from Pseudomonas AM1: existence of two residues binding the prosthetic group.

DOI  10.1093/oxfordjournals.jbchem.a134144,

Publication Year  1983

PubMed ID  6841324,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.