SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02251

Signal sequence   MHFLAAAFLLLTLSASALA

Length  19

Organism  Sus scrofa (Pig)

UniProt ID  O97763,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02251.cif

Structure  SPKB02251.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1961.39284

Aliphatic index  154.7368421

Isoelectric point  7.550323994

Charge (pH=7)   0.08889339

Topological polar surface area  676.49

Aromaticity  0.105263158

Average rotatable bonds  3.210526316

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -2.9096

Hydropathy 



Literature Information


Title  A porcine homolog of the major secretory protein of human epididymis, HE1, specifically binds cholesterol.

DOI  10.1016/s1388-1981(99)00070-0,

Publication Year  1999

PubMed ID  10366780,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.