Peptide-Information

General Information

SPKB ID SPKB02246

Signal sequence MLPCASCLPGSLLLWALLLLLLG

Length 23

Organism Homo sapiens (Human)

UniProt ID O95967,

Motif 1..23

Activity Information

Pathway SRP-dependent

Natural/Artificial Natural

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB02246.cif

Structure SPKB02246.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2411.10324

Aliphatic index 195.2173913

Isoelectric point 5.826007312

Charge (pH=7) -0.125965132

Topological polar surface area 742.19

Aromaticity 0.043478261

Average rotatable bonds 3.217391304

Number of hydrogen bond donors 27

Number of hydrogen bond acceptors 29

X logP energy 0.2073

Hydropathy

Literature Information

Title Fibulin-3, -4, and -5 are highly susceptible to proteolysis, interact with cells and heparin, and form multimers.

Publication Year 2013

PubMed ID 23782690,

Patent ID NA,