SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02244

Signal sequence   MAVFLQLLPLLLSRAQG

Length  17

Organism  Homo sapiens (Human)

UniProt ID  O95866,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02244.cif

Structure  SPKB02244.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1870.32674

Aliphatic index  166.4705882

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  688.44

Aromaticity  0.058823529

Average rotatable bonds  3.588235294

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  23

X logP energy  -2.95253

Hydropathy 



Literature Information


Title  Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

DOI  10.1038/nbt810,

Publication Year  2003

PubMed ID  12665801,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.