SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02243

Signal sequence   MHLLLFQLLVLLPLGKT

Length  17

Organism  Homo sapiens (Human)

UniProt ID  O95813,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02243.cif

Structure  SPKB02243.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1949.51184

Aliphatic index  200.5882353

Isoelectric point  9.702001779

Charge (pH=7)   1.088598356

Topological polar surface area  638.15

Aromaticity  0.058823529

Average rotatable bonds  3.764705882

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  23

X logP energy  1.0544

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.