SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02241

Signal sequence   MSLLPRRAPPVSMRLLAAALLLLLLALYTARVDG

Length  34

Organism  Homo sapiens (Human)

UniProt ID  O95715,

Motif  1..34



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02241.cif

Structure  SPKB02241.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3676.56994

Aliphatic index  160.8823529

Isoelectric point  12.02979393

Charge (pH=7)   2.997567124

Topological polar surface area  1363.07

Aromaticity  0.029411765

Average rotatable bonds  3.441176471

Number of hydrogen bond donors  49

Number of hydrogen bond acceptors  46

X logP energy  -7.16712

Hydropathy 



Literature Information


Title  Molecular cloning and characterization of a novel CXC chemokine macrophage inflammatory protein-2 gamma chemoattractant for human neutrophils and dendritic cells.

DOI  10.4049/jimmunol.165.5.2588,

Publication Year  2000

PubMed ID  10946286,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.