SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02239

Signal sequence   MRPGAPGPLWPLPWGALAWAVGFVSS

Length  26

Organism  Homo sapiens (Human)

UniProt ID  O95633,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02239.cif

Structure  SPKB02239.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2721.21764

Aliphatic index  82.69230769

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  896.6

Aromaticity  0.153846154

Average rotatable bonds  2.730769231

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -3.47953

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.