General Information
SPKB ID SPKB02238
Signal sequence MRALEGPGLSLLCLVLALPALLPVPAVRG
Length 29
Organism Homo sapiens (Human)
UniProt ID O95407,
Motif 1..29
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02238.cif
Physicochemical Information
Molecular weight 2940.68544
Aliphatic index 164.8275862
Isoelectric point 8.549845238
Charge (pH=7) 0.937778084
Topological polar surface area 1024.29
Aromaticity 0
Average rotatable bonds 3.103448276
Number of hydrogen bond donors 35
Number of hydrogen bond acceptors 36
X logP energy -4.57926
Hydropathy
Literature Information
Title A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis.
Publication Year 1999
PubMed ID 10318773,
Patent ID NA,