General Information
SPKB ID SPKB02237
Signal sequence MLRRPAPALAPAARLLLAGLLCGGGVWA
Length 28
Organism Homo sapiens (Human)
UniProt ID O94985,
Motif 1..28
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02237.cif
Physicochemical Information
Molecular weight 2815.48004
Aliphatic index 132.8571429
Isoelectric point 12.19926402
Charge (pH=7) 2.93599965
Topological polar surface area 1024.14
Aromaticity 0.035714286
Average rotatable bonds 3.035714286
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 34
X logP energy -6.15319
Hydropathy 
Literature Information
Title Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation.
Publication Year 2004
PubMed ID 15037614,
Patent ID NA,
