SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02234

Signal sequence   MACGGKRLLFLALAWVLLAHLCSQAEA

Length  27

Organism  Mus musculus (Mouse)

UniProt ID  O89093,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02234.cif

Structure  SPKB02234.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2886.52734

Aliphatic index  134.0740741

Isoelectric point  8.241258298

Charge (pH=7)   0.966420736

Topological polar surface area  1052.93

Aromaticity  0.074074074

Average rotatable bonds  3.481481481

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  37

X logP energy  -5.57593

Hydropathy 



Literature Information


Title  Selective expression of liver and activation-regulated chemokine (LARC) in intestinal epithelium in mice and humans.

DOI  10.1002/(SICI)1521-4141(199902)29:02<633::AID-IMMU633>3.0.CO;2-I,

Publication Year  1999

PubMed ID  10064080,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.