SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02233

Signal sequence   MARLAAALWSLCVTTVLVTSATQG

Length  24

Organism  Rattus norvegicus (Rat)

UniProt ID  O88917,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02233.cif

Structure  SPKB02233.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2463.93614

Aliphatic index  122.0833333

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  974.78

Aromaticity  0.041666667

Average rotatable bonds  3.208333333

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  35

X logP energy  -10.12453

Hydropathy 



Literature Information


Title  alpha-Latrotoxin stimulates exocytosis by the interaction with a neuronal G-protein-coupled receptor.

DOI  10.1016/s0896-6273(00)80332-3,

Publication Year  1997

PubMed ID  9208860,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.