General Information
SPKB ID SPKB02233
Signal sequence MARLAAALWSLCVTTVLVTSATQG
Length 24
Organism Rattus norvegicus (Rat)
UniProt ID O88917,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02233.cif
Physicochemical Information
Molecular weight 2463.93614
Aliphatic index 122.0833333
Isoelectric point 8.549912035
Charge (pH=7) 0.936006272
Topological polar surface area 974.78
Aromaticity 0.041666667
Average rotatable bonds 3.208333333
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 35
X logP energy -10.12453
Hydropathy
Literature Information
Title alpha-Latrotoxin stimulates exocytosis by the interaction with a neuronal G-protein-coupled receptor.
DOI 10.1016/s0896-6273(00)80332-3,
Publication Year 1997
PubMed ID 9208860,
Patent ID NA,