SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02232

Signal sequence   MNGVAAALLVWILTSPSSS

Length  19

Organism  Mus musculus (Mouse)

UniProt ID  O88188,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  3M7O,

Predicted Structure ID  SPKB02232.cif

Structure  SPKB02232.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1917.25054

Aliphatic index  128.4210526

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  738.36

Aromaticity  0.052631579

Average rotatable bonds  3.052631579

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -7.4791

Hydropathy 



Literature Information


Title  Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression.

DOI  NA,

Publication Year  1998

PubMed ID  9686597,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.