SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02231

Signal sequence   MNRIYSLRYSAVARGFIAVSEFARKCVHKSVRRLCFPVLLLIPVLFSAGSLA

Length  52

Organism  Escherichia coli

UniProt ID  O88093,

Motif  1..52



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02231.cif

Structure  SPKB02231.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5828.04624

Aliphatic index  120

Isoelectric point  11.43124759

Charge (pH=7)   6.964408317

Topological polar surface area  2224.19

Aromaticity  0.115384615

Average rotatable bonds  3.634615385

Number of hydrogen bond donors  84

Number of hydrogen bond acceptors  75

X logP energy  -16.10778

Hydropathy 



Literature Information


Title  Characterization of a hemoglobin protease secreted by the pathogenic Escherichia coli strain EB1.

DOI  10.1084/jem.188.6.1091,

Publication Year  1998

PubMed ID  9743528,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.