General Information
SPKB ID SPKB02226
Signal sequence MRGTPKTHLLAFSLLCLLSKVRT
Length 23
Organism Homo sapiens (Human)
UniProt ID O76076,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02226.cif
Physicochemical Information
Molecular weight 2586.19564
Aliphatic index 118.6956522
Isoelectric point 11.65160089
Charge (pH=7) 4.026321984
Topological polar surface area 1000.4
Aromaticity 0.043478261
Average rotatable bonds 3.739130435
Number of hydrogen bond donors 38
Number of hydrogen bond acceptors 36
X logP energy -8.04306
Hydropathy
Literature Information
Title Signal peptide prediction based on analysis of experimentally verified cleavage sites.
DOI 10.1110/ps.04682504,
Publication Year 2004
PubMed ID 15340161,
Patent ID NA,