SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02220

Signal sequence   MNKIYSIKYSAATGGLIAVSELAKKVICKTNRKISAALLSLAVISYTNIIYA

Length  52

Organism  Escherichia coli O44:H18 (strain 042 / EAEC)

UniProt ID  O68900,

Motif  1..52



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02220.cif

Structure  SPKB02220.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5578.69834

Aliphatic index  129.6153846

Isoelectric point  10.3279507

Charge (pH=7)   5.932609535

Topological polar surface area  2195

Aromaticity  0.076923077

Average rotatable bonds  3.653846154

Number of hydrogen bond donors  80

Number of hydrogen bond acceptors  79

X logP energy  -18.78703

Hydropathy 



Literature Information


Title  Pet, an autotransporter enterotoxin from enteroaggregative Escherichia coli.

DOI  10.1128/IAI.66.7.3155-3163.1998,

Publication Year  1998

PubMed ID  9632580,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.