General Information
SPKB ID SPKB02215
Signal sequence MIRNWLTIFILFPLKLVEKCES
Length 22
Organism Homo sapiens (Human)
UniProt ID O60931,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8DKE,
Predicted Structure ID SPKB02215.cif
Physicochemical Information
Molecular weight 2694.33194
Aliphatic index 137.2727273
Isoelectric point 8.540441717
Charge (pH=7) 0.93896645
Topological polar surface area 953.51
Aromaticity 0.136363636
Average rotatable bonds 4.045454545
Number of hydrogen bond donors 34
Number of hydrogen bond acceptors 33
X logP energy -1.54433
Hydropathy
Literature Information
Title Impact of Cystinosin Glycosylation on Protein Stability by Differential Dynamic Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC).
Publication Year 2017
PubMed ID 28082515,
Patent ID NA,