General Information
SPKB ID SPKB02213
Signal sequence MGKLIRMGPQERWLLRTKRLHWSRLLFLLGMLIIGSTYQHLRRPRGLSSLWAAVSSHQPIKLASR
Length 65
Organism Homo sapiens (Human)
UniProt ID O60721,
Motif 1..65
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02213.cif
Physicochemical Information
Molecular weight 7620.17194
Aliphatic index 111.0769231
Isoelectric point 12.80782217
Charge (pH=7) 11.27072138
Topological polar surface area 3036.79
Aromaticity 0.076923077
Average rotatable bonds 3.923076923
Number of hydrogen bond donors 113
Number of hydrogen bond acceptors 98
X logP energy -22.75437
Hydropathy 
Literature Information
Title The retinal rod Na(+)/Ca(2+),K(+) exchanger contains a noncleaved signal sequence required for translocation of the N terminus.
Publication Year 1999
PubMed ID 10608890,
Patent ID NA,
