SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02210

Signal sequence   MSRTAYTVGALLLLLGTLLPAAEG

Length  24

Organism  Homo sapiens (Human)

UniProt ID  O60565,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02210.cif

Structure  SPKB02210.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2431.91634

Aliphatic index  142.5

Isoelectric point  6.403313374

Charge (pH=7)   -0.001094303

Topological polar surface area  924.18

Aromaticity  0.041666667

Average rotatable bonds  3.208333333

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  33

X logP energy  -7.02843

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.