General Information
SPKB ID SPKB02209
Signal sequence MRTGWATPRRPAGLLMLLFWFFDLAEP
Length 27
Organism Homo sapiens (Human)
UniProt ID O60449,
Motif 1..27
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 7JPU,
Predicted Structure ID SPKB02209.cif
Physicochemical Information
Molecular weight 3193.82074
Aliphatic index 83.33333333
Isoelectric point 10.30863985
Charge (pH=7) 1.000195972
Topological polar surface area 1125.89
Aromaticity 0.185185185
Average rotatable bonds 3.518518519
Number of hydrogen bond donors 40
Number of hydrogen bond acceptors 37
X logP energy -3.35209
Hydropathy
Literature Information
Title The gp200-MR6 molecule which is functionally associated with the IL-4 receptor modulates B cell phenotype and is a novel member of the human macrophage mannose receptor family.
DOI 10.1002/(SICI)1521-4141(199812)28:12<4071::AID-IMMU4071>3.0.CO;2-O,
Publication Year 1998
PubMed ID 9862343,
Patent ID NA,