SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02208

Signal sequence   MRALWIVAVLLVGVEG

Length  16

Organism  Deinagkistrodon acutus (Hundred-pace snake) (Agkistrodon acutus)

UniProt ID  O57385,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02208.cif

Structure  SPKB02208.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1726.15344

Aliphatic index  182.5

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  614.81

Aromaticity  0.0625

Average rotatable bonds  3.4375

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  20

X logP energy  -0.61353

Hydropathy 



Literature Information


Title  Characterization, crystallization and preliminary X--ray diffraction analysis of acutohaemolysin, a haemolytic toxin from Agkistrodon acutus venom.

DOI  10.1107/s0907444900005643,

Publication Year  2000

PubMed ID  10930841,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.