SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02207

Signal sequence   MAFHSMLLVFLAGLVFLTEA

Length  20

Organism  Crocodylus porosus (Saltwater crocodile) (Estuarine crocodile)

UniProt ID  O55245,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02207.cif

Structure  SPKB02207.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2210.72064

Aliphatic index  141.5

Isoelectric point  5.363507222

Charge (pH=7)   -0.909331487

Topological polar surface area  722.66

Aromaticity  0.15

Average rotatable bonds  3.5

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  27

X logP energy  -0.7189

Hydropathy 



Literature Information


Title  Crocodile transthyretin: structure, function, and evolution.

DOI  10.1152/ajpregu.00042.2002,

Publication Year  2002

PubMed ID  12228058,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.