General Information
SPKB ID SPKB02206
Signal sequence MNLPSTKVPWAAVTLLLLLLLPPALLSLGVDA
Length 32
Organism Rattus norvegicus (Rat)
UniProt ID O55232,
Motif 1..32
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02206.cif
Physicochemical Information
Molecular weight 3341.13924
Aliphatic index 173.75
Isoelectric point 6.337367167
Charge (pH=7) -0.00186425
Topological polar surface area 1133.38
Aromaticity 0.03125
Average rotatable bonds 3.15625
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 41
X logP energy -3.6596
Hydropathy
Literature Information
Title Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.
DOI 10.1016/s0092-8674(00)80949-6,
Publication Year 1998
PubMed ID 9491897,
Patent ID NA,