SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02201

Signal sequence   MLRGIQALSRPLTRVYRALAVIGVLAASLLASWVGAVPQVGLA

Length  43

Organism  Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

UniProt ID  O53361,

Motif  1..43



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cytoplasmic vesicle

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02201.cif

Structure  SPKB02201.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4459.40914

Aliphatic index  149.7674419

Isoelectric point  12.50176958

Charge (pH=7)   3.99712064

Topological polar surface area  1718.66

Aromaticity  0.046511628

Average rotatable bonds  3.302325581

Number of hydrogen bond donors  62

Number of hydrogen bond acceptors  56

X logP energy  -12.77872

Hydropathy 



Literature Information


Title  Secretion of an acid phosphatase (SapM) by Mycobacterium tuberculosis that is similar to eukaryotic acid phosphatases.

DOI  10.1128/JB.182.23.6850-6853.2000,

Publication Year  2000

PubMed ID  11073936,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.